Characterization of resistance and virulence factors in livestock-associated methicillin-resistant Staphylococcus aureus

A study in Nigeria found that livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in cows is linked to severe infections, antimicrobial resistance (AMR), and virulence factors. The study analyzed 400 samples collected between 2018 and 2019, revealing 63.5% for Staphylococcus aureus and 55% for MRSA. Of the 76 mecA-positive MRSA isolates, 64.5% exhibited multidrug resistance (MDR), while the remaining were sensitive to specific antimicrobials. Key virulence genes were prevalent, along with AMR genes. The study underscored the importance of ongoing surveillance for informed treatment strategies, AMR policies, and control measures against MDR staphylococcal infections.